Opzelura The first drug to restore pigmentation for vitiligo patients - 9oole

Opzelura The first drug to restore pigmentation for vitiligo patients

Opzelura The first drug to restore pigmentation for vitiligo patients


What is the drug Upzilora and what is its role in vitiligo?

Vitiligo is a disease in which there is a problem in the immune system that makes it attack the melanocytes responsible for producing the melanin pigment in the skin, which causes the disappearance of skin pigmentation in certain areas of the body . Ruxolitinib can improve the condition by re-pigmentation of these areas. [1]

This drug is a drug used in certain cases of simple and moderate atopic dermatitis (eczema) in which other drugs cannot be used, and the US Food and Drug Administration (FDA) has approved its use for non-segmental vitiligo, which is the most common type of vitiligo, to be the first drug approved Approved for re-pigmentation for vitiligo patients. [1]

What is the truth about the effectiveness of the drug Upzilora for vitiligo?

The efficacy of Upzilora for repigmentation in non-segmental vitiligo has been demonstrated in two studies that showed the role of this drug in repigmentation by 75% in approximately 50% of the subjects who participated in these studies within a period of 6 months to a year from the start of using the drug. Demonstrated efficacy in subjects 12 years of age and older with non-segmental vitiligo. [2]

What distinguishes Upzelora from other vitiligo medications?

Upsilora is the only drug whose ability to re-pigmentation has been proven for people with vitiligo, as there is another drug approved by the US Food and Drug Administration, but it works by removing pigmentation in places that contain pigment in the body in order to unify the skin color. [3]

Upzelora also has the advantage of being able to use it on the face . Unlike other drugs that were previously used for vitiligo, it does not cause annoying or dangerous side effects on the face. [3]

How is Upzelora Repigmentation used?

Upzelora is available in the form of a cream that is applied topically to the skin. A thin layer of cream should be applied twice a day to the areas affected by vitiligo, up to 10% of the body surface area. However, you should consult a doctor before using it to ensure that the dosage is appropriate in your case and that the drug does not conflict. with you. [4]

The results usually need about 24 weeks (6 months) to appear, and in the event that no improvement is noticed, you must see a doctor to re-evaluate the condition and determine the cause of the problem. [4]

Does the use of Upzelora cause side effects?

Among the side effects that were observed in studies when using the drug Upsilora: [4]

  • Acne appears where the cream is applied.
  • Itching at the place of application of the cream.
  • Nasopharyngitis.
  • Headache.
  • Urinary tract infections.
  • Redness of the skin at the site of application of the cream.
  • High body temperature.

However, it should be noted that this does not mean that these symptoms will appear in everyone, as the symptoms that may appear and their severity differ from one person to another, in addition to the possibility of the drug causing other more serious symptoms, so it is important not to use it without consulting a doctor to ensure its safety . your condition. [1]


  1. ^ abc “FDA approves topical treatment addressing repigmentation in vitiligo in patients aged 12 and older” , fda , Retrieved 8/14/2022. Edited.
  2. “FDA Approves First At-Home Treatment for Skin Repigmentation in People With Common Type of Vitiligo” , healthline , Retrieved 8/14/2022. Edited.
  3. ^ Becky Upham (22/7/2022), “FDA Approves New Vitiligo Treatment, Ruxolitinib (Opzelura)”, everydayhealth, Retrieved 14/8/2022. Edited.
  4. ^ “HIGHLIGHTS OF PRESCRIBING INFORMATION”, opzelura, Retrieved 14/8/2022. Edited.

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